The symptoms of general weariness and prostration produced by the drug have been utilized in prescribing it homeopathically as a general tonic, often with very marked beneficial and prompt effect. In diphtheria with great prostration, cases that are prolonged, especially, and in malarial affections, neuralgia, etc, it has been found curative. Asthmatic attacks which recur periodically, with great prostration. Icy skin. Pressure in the solar plexus, with tender spine back of it.

Dose.--Second and third trituration.

Extremities.--Weak limbs. Coldness of hands and feet, knees and limbs. Tearing pains.

Eyes.--Intense photophobia and orbicular spasm; gushing hot tears. Flickering with pain and lachrymation.

Fever.--Continuous, with weakness. System depleted.

Head.--Tired feeling. Head feels too full. Throbbing. Great anxiety. Great irritability. Vertigo; worse looking up. Dull, heavy headache, frontal and occipital. Darting pains running up into head.

Heart.--Palpitation. Sensation as if heart stopped. Suffocative attacks, occurring in periodical paroxysms. Must have open air. Short of breath on ascending; cardiac dyspnea; circulatory weakness after acute infections; early myocardial degeneration.

Mouth.--Tongue thickly furred; yellow, slimy coating. Bitter taste. No appetite.

Relationship.--Compare: Chininum; also Ferrum Citricum (in nephritis with great anemia; acid dyspepsia in chlorosis. Morbus maculosus Werlhoffii); Chinin mur (in severe neuralgic pains around eyes, with chills; exaggerated sensitiveness to alcohol and tobacco; prostration and restlessness). enothera (effortless diarrhea with nervous exhaustion; incipient hydrocephaloid). Macrozamia spiralis (extreme debility after illness; collapse).

Sleep.--Sleeplessness due to nervous causes (Single dose of 5th or 6th potency).

Stomach.--Alternation of hyperacidity and decrease of acid. Hyperchlorhydria (Robinia; Arg nit; Orexine tannate). Thirst for water, yet it disturbs. Anorexia. Eggs produce diarrhea.